This study aims to discuss an experience in the treatment of lacerations in different parts of the skin in emergency surgery, and summarize the clinical application value of medical adhesives for wound debridement and adhesion. The signs for application, usage methods and steps in the treatment of wounds, as well as the effect observation recorded in literatures and case records were reviewed. Application of medical adhesives in the treatment of head and face skin lacerations can reduce scars. It can also reduce pain caused by trauma, and the incidence of wound abscess and inflammation in the treatment of limb and nail bed injuries. The application of medical adhesives for debridement simplifies the operation and shortens operation time, saves the requirement of stitch removal, and reduces the patient's pain and difficulties, and patient visits. The standard use of medical adhesives can achieve a better effect on trauma repair, and avoid erythema, induration, scar hyperplasia and other needle reactions in debridement of skin lacerations; achieving the cosmetic repair of trauma. By reviewing past experiences in the use of medical adhesives, this study summarizes the methods and precautions for the application of medical adhesives for injuries in different parts of the skin.