单位:[1]Yunnan Center for Disease Control and Prevention, Kunming 650011,Yunnan, China[2]Huangpi District Center for Disease Control and Prevention,Wuhan 432200, China[3]Lincang City Center for Disease Control andPrevention, Lincang 677000, Yunnan, China[4]Beijing Tropical MedicineResearch Institute, Beijing Friendship Hospital, Capital Medical University,Beijing 100050, China首都医科大学附属北京友谊医院[5]Beijing Key Laboratory for Research on Preventionand Treatment of Tropical Diseases, Capital Medical University, Beijing100050, China[6]Chinese Center for Disease Control and Prevention, Beijing102206, China
Background: Two months after the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, tens of thousands of hospitalized patients had recovered, and little is known about the follow-up of the recovered patients. Methods: The clinical characteristics, reverse transcriptase-polymerase chain reaction (RT-PCR) results from throat swab specimens and the results of serological COVID-19 rapid diagnostic test (RDT) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were retrospectively reviewed for a total of 758 recovered patients who were previously hospitalized in 17 hospitals and quarantined at 32 rehabilitation stations in Wuhan, China. Results: In total, 59 patients (7.78%) had recurrent positive findings for COVID-19 on RT-PCR from throat swabs. With regard to antibody detection, 50/59 (84.75%) and 4/59 (6.78%) patients had positive IgG or dual positive IgG/IgM RDT results, respectively. Conclusions: Some patients who had been quarantined and had subsequently recovered from COVID-19 had recurrent positive RT-PCR results for SARS-CoV-2, and the possibility of transmission of the virus by recovered patients needs further investigation.
第一作者单位:[1]Yunnan Center for Disease Control and Prevention, Kunming 650011,Yunnan, China
共同第一作者:
通讯作者:
通讯机构:[4]Beijing Tropical MedicineResearch Institute, Beijing Friendship Hospital, Capital Medical University,Beijing 100050, China[5]Beijing Key Laboratory for Research on Preventionand Treatment of Tropical Diseases, Capital Medical University, Beijing100050, China
推荐引用方式(GB/T 7714):
Tie-Jun Shui,Chao Li,Hong-bing Liu,et al.Characteristics of recovered COVID-19 patients with recurrent positive RT-PCR findings in Wuhan, China: a retrospective study[J].BMC INFECTIOUS DISEASES.2020,20(1):doi:10.1186/s12879-020-05463-z.
APA:
Tie-Jun Shui,Chao Li,Hong-bing Liu,Xiaohua Chen&Bi-ke Zhang.(2020).Characteristics of recovered COVID-19 patients with recurrent positive RT-PCR findings in Wuhan, China: a retrospective study.BMC INFECTIOUS DISEASES,20,(1)
MLA:
Tie-Jun Shui,et al."Characteristics of recovered COVID-19 patients with recurrent positive RT-PCR findings in Wuhan, China: a retrospective study".BMC INFECTIOUS DISEASES 20..1(2020)