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Characteristics of recovered COVID-19 patients with recurrent positive RT-PCR findings in Wuhan, China: a retrospective study

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单位: [1]Yunnan Center for Disease Control and Prevention, Kunming 650011,Yunnan, China [2]Huangpi District Center for Disease Control and Prevention,Wuhan 432200, China [3]Lincang City Center for Disease Control andPrevention, Lincang 677000, Yunnan, China [4]Beijing Tropical MedicineResearch Institute, Beijing Friendship Hospital, Capital Medical University,Beijing 100050, China [5]Beijing Key Laboratory for Research on Preventionand Treatment of Tropical Diseases, Capital Medical University, Beijing100050, China [6]Chinese Center for Disease Control and Prevention, Beijing102206, China
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关键词: SARS-CoV-2 COVID-19 Recurrent RT-PCR

摘要:
Background: Two months after the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, tens of thousands of hospitalized patients had recovered, and little is known about the follow-up of the recovered patients. Methods: The clinical characteristics, reverse transcriptase-polymerase chain reaction (RT-PCR) results from throat swab specimens and the results of serological COVID-19 rapid diagnostic test (RDT) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were retrospectively reviewed for a total of 758 recovered patients who were previously hospitalized in 17 hospitals and quarantined at 32 rehabilitation stations in Wuhan, China. Results: In total, 59 patients (7.78%) had recurrent positive findings for COVID-19 on RT-PCR from throat swabs. With regard to antibody detection, 50/59 (84.75%) and 4/59 (6.78%) patients had positive IgG or dual positive IgG/IgM RDT results, respectively. Conclusions: Some patients who had been quarantined and had subsequently recovered from COVID-19 had recurrent positive RT-PCR results for SARS-CoV-2, and the possibility of transmission of the virus by recovered patients needs further investigation.

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出版当年[2019]版:
大类 | 3 区 医学
小类 | 3 区 传染病学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 传染病学
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出版当年[2018]版:
Q3 INFECTIOUS DISEASES
最新[2023]版:
Q2 INFECTIOUS DISEASES

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2018版] 出版当年五年平均[2014-2018] 出版前一年[2017版] 出版后一年[2019版]

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第一作者单位: [1]Yunnan Center for Disease Control and Prevention, Kunming 650011,Yunnan, China
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通讯机构: [4]Beijing Tropical MedicineResearch Institute, Beijing Friendship Hospital, Capital Medical University,Beijing 100050, China [5]Beijing Key Laboratory for Research on Preventionand Treatment of Tropical Diseases, Capital Medical University, Beijing100050, China
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