单位：[1]Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, China[2]Emergency Department, China-Japan Friendship Hospital, Beijing, China
Materials capable of ultrasonic imaging in vivo are essential for the development of ultrasound visualized interventional catheters. In the present research, hollow glass beads (HGB) were added to polyurethane as ultrasonic image-enhancing agent to obtain composite with improved ultrasonic visibility within body tissues. The experimental results show that with the increase of the volume percentage of HGB (V-HGB) in the composites, the clarity of the ultrasonic images of the composite samples gradually improves. For ultrasonic imaging, a proper V-HGB would be 6% to 10%. The particle size (25-65 mu m) of the HGB has almost no effect on the imaging of the composites at the same loading level of the glass beads. The result obtained in the experiments conducted in pig body confirmed that TPU/HGB composite sample could provide significant enhanced ultrasonic imaging compared with pure polyurethane sample and the commercial interventional catheter sample used. Medical safety of the composite was briefly investigated as well by testing the extraction solution of the composite sample.
基金：
Animal Ethical and Welfare Committee [160301]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [51573211]
第一作者单位：[1]Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[1]Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, China[2]Emergency Department, China-Japan Friendship Hospital, Beijing, China[*1]Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, China[*2]Emergency Department, Beijing, China.
推荐引用方式(GB/T 7714)：
Gao Weining,Lian Rui,Chen Xiaonong,et al.Enhanced ultrasonic imaging property of polyurethane filled with hollow glass beads[J].POLYMER COMPOSITES.2020,41(7):2588-2597.doi:10.1002/pc.25557.
APA：
Gao, Weining,Lian, Rui,Chen, Xiaonong,Yan, Shentao,Zhang, Suqiao&Zhang, Guoqiang.(2020).Enhanced ultrasonic imaging property of polyurethane filled with hollow glass beads.POLYMER COMPOSITES,41,(7)
MLA：
Gao, Weining,et al."Enhanced ultrasonic imaging property of polyurethane filled with hollow glass beads".POLYMER COMPOSITES 41..7(2020):2588-2597
