单位：[1]Department of Clinical Laboratory, China-Japan Friendship Hospital, P. R. of CHINA[2]College of Information Science and Technology, Beijing University of Chemical Technology, P. R.of CHINA[3]Beijing Advanced Innovation Center for Soft Matter Science and Engineering, P. R. of CHINA
This work for the first time demonstrates a single-cell impedance micro-cytometer with 3D differential electrodes and fluidic sidewalls completely made of silver-PDMS composites (AgPDMS). Such monolithically integrated electro-fluidic structure is an outcome of one-step molding from a readily used master, obviating extra sacrificial layer patterning as required in the existing device incorporating AgPDMS electrodes. To maintain maximum sensitivity, the device exploits 3D sidewall electrode configured differentially with minimized sensing volume between the electrodes. The micro-cytometer has been showcased here for flow impedance measurement of polystyrene microspheres at multiple frequencies, as well as real-time differentiation between 7 mu m beads and human red blood cells (RBCs) featuring similar size.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [61804007]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [buctrc201809, XK1802-4]; Research Fund to the Top Scientific and Technological Innovation Team from Beijing University of Chemical Technology [buctylkjcx06]
语种：
外文
被引次数：
WOS：
第一作者：
第一作者单位：[1]Department of Clinical Laboratory, China-Japan Friendship Hospital, P. R. of CHINA
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推荐引用方式(GB/T 7714)：
Han Chengwu,Liang Ziheng,Yu Duli,et al.A SINGLE-CELL IMPEDANCE MICRO-CYTOMETER FEATURING 3D ELECTRO-FLUIDIC STRUCTURES MONOLITHICALLY INTEGRATED WITHIN SILVER PDMS[J].2019 20TH INTERNATIONAL CONFERENCE on SOLID-STATE SENSORS, ACTUATORS and MICROSYSTEMS & EUROSENSORS XXXIII (TRANSDUCERS & EUROSENSORS XXXIII).2019,9-12.
APA：
Han, Chengwu,Liang, Ziheng,Yu, Duli&Xing, Xiaoxing.(2019).A SINGLE-CELL IMPEDANCE MICRO-CYTOMETER FEATURING 3D ELECTRO-FLUIDIC STRUCTURES MONOLITHICALLY INTEGRATED WITHIN SILVER PDMS.2019 20TH INTERNATIONAL CONFERENCE on SOLID-STATE SENSORS, ACTUATORS and MICROSYSTEMS & EUROSENSORS XXXIII (TRANSDUCERS & EUROSENSORS XXXIII),,
MLA：
Han, Chengwu,et al."A SINGLE-CELL IMPEDANCE MICRO-CYTOMETER FEATURING 3D ELECTRO-FLUIDIC STRUCTURES MONOLITHICALLY INTEGRATED WITHIN SILVER PDMS".2019 20TH INTERNATIONAL CONFERENCE on SOLID-STATE SENSORS, ACTUATORS and MICROSYSTEMS & EUROSENSORS XXXIII (TRANSDUCERS & EUROSENSORS XXXIII) .(2019):9-12
