单位：[1]Department of Ophthalmology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong’an Road, Xicheng District, Beijing 100050, People’s Republic of China.临床科室眼科眼科首都医科大学附属北京友谊医院[2]Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.医技科室影像中心放射科首都医科大学附属北京友谊医院[3]Department of Ophthalmology, PLA Army General Hospital, No.5, nanmencang, Dongsishitiao, dongcheng district, Beijing 100000, China.[4]Department of Rheumatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.临床科室风湿内科风湿内科首都医科大学附属北京友谊医院[5]Department of Ophthalmology, PLA General Hospital, No.28, fuxing road, haidian district, Beijing, China100080.
BackgroundThe following study investigates the involvement of optic neuropathy in IgG4-related ophthalmic diseases (IgG4-ROD) based on the magnetic resonance imaging (MRI) data, and different imaging features of IgG4-ROD related optic neuropathy related to other orbital diseases.MethodsThis retrospective study included 225 patients with IgG4-RD admitted at two ophthalmology centers between January 2014 and December 2017. Twenty-six patients had both pre-therapeutic orbital MRI and optic never injury. The causes of optic neuropathy were analyzed, and the special sign in MRI to diagnose IgG4-ROD was also evaluated.ResultsTwelve cases had inflammation of the optic nerve sheath, while 14 cases had compression due to extraocular muscles and pseudo tumor masses. Two cases had hypertrophic cranial pachymeningitis, while one case had hypophysis involving optic chiasma.ConclusionThe most common causes of optic nerve injury in IgG-4 ROD are inflammation of optic nerve sheath, compression of extraocular muscles, pseudo tumor mass and hypertrophic cranial pachymeningitis, and hypophysis involving optic chiasma.
基金：
Beijing Natural Science FoundationBeijing Natural Science Foundation [7162048]; Beijing Municipal Science & Technology CommissionBeijing Municipal Science & Technology Commission [Z171100001017163]; Start Funding of Beijing Friendship Hospital [yyqdkt2016-8]
第一作者单位：[2]Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
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推荐引用方式(GB/T 7714)：
Jing Li,Yan Zhang,Hang Zhou,et al.Magnetic resonance imaging indicator of the causes of optic neuropathy in IgG4-related ophthalmic disease[J].BMC MEDICAL IMAGING.2019,19:doi:10.1186/s12880-019-0347-z.
APA：
Jing Li,Yan Zhang,Hang Zhou,Lei Wang,Zhenchang Wang&Hongyang Li.(2019).Magnetic resonance imaging indicator of the causes of optic neuropathy in IgG4-related ophthalmic disease.BMC MEDICAL IMAGING,19,
MLA：
Jing Li,et al."Magnetic resonance imaging indicator of the causes of optic neuropathy in IgG4-related ophthalmic disease".BMC MEDICAL IMAGING 19.(2019)
