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A new in-line X-ray phase-contrast computed tomography reconstruction algorithm based on adaptive-weighted anisotropic TpV regularization for insufficient data

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单位: [1]School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, People’s Republic of China, [2]The School of Science, Tianjin University of Technology and Education, Tianjin 300222, People’s Republic of China, [3]School of Physics and Information Engineering, Minnan Normal University, 363000 Fujian, People’s Republic of China, [4]School of Information and Communication Engineering, University of Electronic Science and Technology of China, 610054 Sichuan, People’s Republic of China, [5]Radiation Oncology Department, Tianjin Medical University General Hospital, Tianjin 300070, People’s Republic of China, [6]Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, People’s Republic of China.
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关键词: in-line X-ray phase-contrast computed tomography adaptive-weighted anisotropic total p-variation regularization projection onto convex sets radiation dose

摘要:
In-line X-ray phase-contrast computed tomography (IL-PCCT) is a valuable tool for revealing the internal detailed structures in weakly absorbing objects (e.g. biological soft tissues), and has a great potential to become clinically applicable. However, the long scanning time for IL-PCCT will result in a high radiation dose to biological samples, and thus impede the wider use of IL-PCCT in clinical and biomedical imaging. To alleviate this problem, a new iterative CT reconstruction algorithm is presented that aims to decrease the radiation dose by reducing the projection views, while maintaining the high quality of reconstructed images. The proposed algorithm combines the adaptive-weighted anisotropic total p-variation (AwaTpV, 0 < p < 1) regularization technique with projection onto convex sets (POCS) strategy. Noteworthy, the AwaTpV regularization term not only contains the horizontal and vertical image gradients but also adds the diagonal image gradients in order to enforce the directional continuity in the gradient domain. To evaluate the effectiveness and ability of the proposed algorithm, experiments with a numerical phantom and synchrotron IL-PCCT were performed, respectively. The results demonstrated that the proposed algorithm had the ability to significantly reduce the artefacts caused by insufficient data and effectively preserved the edge details under noise-free and noisy conditions, and thus could be used as an effective approach to decrease the radiation dose for IL-PCCT.

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出版当年[2018]版:
大类 | 2 区 物理
小类 | 2 区 仪器仪表 3 区 光学 3 区 物理:应用
最新[2025]版:
大类 | 3 区 物理与天体物理
小类 | 3 区 仪器仪表 3 区 光学 3 区 物理:应用
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出版当年[2017]版:
Q1 PHYSICS, APPLIED Q1 INSTRUMENTS & INSTRUMENTATION Q1 OPTICS
最新[2023]版:
Q2 INSTRUMENTS & INSTRUMENTATION Q2 OPTICS Q3 PHYSICS, APPLIED

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2017版] 出版当年五年平均[2013-2017] 出版前一年[2016版] 出版后一年[2018版]

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第一作者单位: [1]School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, People’s Republic of China,
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