高级检索
当前位置: 首页 > 详情页

Resistant and undertreated hypertension in patients with chronic kidney disease: data from the PATRIOTIC survey

文献详情

资源类型:
WOS体系:

收录情况: ◇ SCIE

单位: [1]Department of Nephrology, Chinese PLA General Hospital, National Clinical Research Center for Kidney Diseases, State Key Laboratory of KidneyDiseases, Chinese PLA Institute of Nephrology, Beijing, China [2]Department of Nephrology, China-Japan Friendship Hospital, Beijing 100029, China [3]Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China [4]Department of Nephrology,Guangdong Provincial People’s Hospital, Guangzhou, Guangdong, China [5]Department of Nephrology, Zhongshan Hospital, Fudan University,Shanghai, China [6]Department of Nephrology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
出处:
ISSN:

关键词: Chinese chronic kidney disease epidemiology resistant hypertension undertreated hypertension

摘要:
Background: Hypertension is prevalent in chronic kidney disease (CKD), but the control of hypertension is suboptimal. We reported the prevalence and characteristics of resistant and undertreated hypertension based on a nationwide survey aiming to improve blood pressure (BP) control. Methods: Resistant hypertension (RH) was defined as BP above the target (<140/90 mm Hg) despite the use of 3 antihypertensive drugs or achieving the target BP by using >= 4 antihypertensive drugs. Undertreated hypertension was defined as uncontrolled hypertension (unCH) using <= 2 drugs. We compared the characteristics and antihypertensive treatment among different groups (including RH and unCH using <= 2 drugs). Multivariable logistic regression was used to detect factors associated with unCH using <= 2 drugs and RH. Results: 4,435 nondialysis CKD patients with hypertension were analyzed, and 36.9% of participants achieved controlled hypertension (CH) using <= 3 drugs, 11.1% met the criteria for RH, and 52% had unCH despite the use of <= 2 antihypertensive drugs. Participants with unCH using <= 2 drugs had low usage of renin-angiotensin system blockers (36.8%) and diuretics (5.5%), which was much lower than participants with CH using <= 3 drugs and RH (P< 0.05). After multivariable adjustment, obesity, advanced CKD stages, urinary protein level of >= 1.5 g/24 h, diabetes, and cardiovascular disease were associated with RH in CKD patients (P< 0.05). Conclusion: Compared with RH, undertreated hypertension contributes more to the unCH in Chinese CKD patients. It is important to ensure adequate antihypertensive treatment, including choosing antihypertensive drugs, that guidelines recommended.

基金:
语种:
被引次数:
WOS:
中科院(CAS)分区:
出版当年[2017]版:
大类 | 4 区 医学
小类 | 4 区 外周血管病 4 区 药学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 外周血管病 4 区 药学
JCR分区:
出版当年[2016]版:
Q4 PHARMACOLOGY & PHARMACY Q4 PERIPHERAL VASCULAR DISEASE
最新[2023]版:
Q3 PERIPHERAL VASCULAR DISEASE Q3 PHARMACOLOGY & PHARMACY

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2016版] 出版当年五年平均[2012-2016] 出版前一年[2015版] 出版后一年[2017版]

第一作者:
第一作者单位: [1]Department of Nephrology, Chinese PLA General Hospital, National Clinical Research Center for Kidney Diseases, State Key Laboratory of KidneyDiseases, Chinese PLA Institute of Nephrology, Beijing, China
共同第一作者:
通讯作者:
通讯机构: [1]Department of Nephrology, Chinese PLA General Hospital, National Clinical Research Center for Kidney Diseases, State Key Laboratory of KidneyDiseases, Chinese PLA Institute of Nephrology, Beijing, China [*1]28 Fuxing Road, Haidian District, Beijing 100853, China
推荐引用方式(GB/T 7714):
APA:
MLA:

资源点击量:1320 今日访问量:0 总访问量:816 更新日期:2025-04-01 建议使用谷歌、火狐浏览器 常见问题

版权所有:重庆聚合科技有限公司 渝ICP备12007440号-3 地址:重庆市两江新区泰山大道西段8号坤恩国际商务中心16层(401121)