详情页 - 聚合机构库演示平台

当前位置：首页 > 详情页

Glycocalyx damage estimated using colloidal iron staining

文献详情

资源类型：

WOS体系：

收录情况： ◇ SCIE

作者：

单位： [1]Osaka Univ, Grad Sch Med, Dept Adv Technol Transplantat, Suita, Osaka 5650871, Japan [2]Osaka Univ, Grad Sch Med, Dept Urol, Osaka, Japan [3]Osaka Univ, Grad Sch Med, Dept Nephrol, Osaka, Japan [4]Capital Med Univ, Beijing Friendship Hosp, Beijing, Peoples R China [5]Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Human Morphol, Okayama, Japan

出处：

DOI：

ISSN：

关键词： glycocalyx transplantation humoral rejection chronic allograft nephropathy cyclosporine

摘要：

Anionic constituents in the peritubular capillary basement membranes and the glomerular endothelial cells have been demonstrated to function as a size- and charge-selective barrier. Cationic colloidal iron staining of human biopsy specimens revealed a glycocalyx on the surface of the glomerular basement membrane (GBM), peritubular capillary (PTC) endothelial cells, and brush border of the tubular epithelial cells of normal kidney. However, the glycocalyx was abolished in the PTC wall of C4d-positive acute humoral rejected kidney, and in the GBM as well as the PTC wall of a chronic, allograft, nephropathy kidney. In addition, cyclosporine eliminated the glycocalyx in the PTC wall, while treatment with heparin inhibited the elimination of the PTC glycocalyx. In conclusion, the glycocalyx on the surface of the GBM and PTC is an important component in the endothelial cell barrier.

语种：

被引次数：

WOS：

中科院(CAS)分区：

出版当年[2007]版：

大类 | 3 区生物

最新[2025]版：

大类 | 4 区医学

小类 | 3 区移植 4 区细胞与组织工程 4 区医学：研究与实验

JCR分区：

出版当年[2006]版：

Q1 TRANSPLANTATION Q2 CELL BIOLOGY

最新[2024]版：

Q2 MEDICINE, RESEARCH & EXPERIMENTAL Q2 TRANSPLANTATION Q3 CELL & TISSUE ENGINEERING

影响因子： 最新[2024版] 3.2 最新五年平均[2021-2025] 3.4 出版当年[2006版] 3.482 出版当年五年平均[2002-2006] 0 出版前一年[2005版] 3.481 出版后一年[2007版] 3.871

第一作者：

第一作者单位： [1]Osaka Univ, Grad Sch Med, Dept Adv Technol Transplantat, Suita, Osaka 5650871, Japan [4]Capital Med Univ, Beijing Friendship Hosp, Beijing, Peoples R China

通讯作者：

通讯机构： [1]Osaka Univ, Grad Sch Med, Dept Adv Technol Transplantat, Suita, Osaka 5650871, Japan [3]Osaka Univ, Grad Sch Med, Dept Nephrol, Osaka, Japan [*1]Osaka Univ, Grad Sch Med, Dept Adv Technol Transplantat, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Bromocriptine as an adjuvant to cyclosporine immunosuppression after renal transplantation [2]THE THERAPEUTIC WINDOW OF CYCLOSPORINE IN CHINESE RECIPIENTS OF RENAL-TRANSPLANTATION [3]肾移植术后抗感染治疗期间环孢素血药浓度监测与剂量调整1例 [4]Cyclosporine Combined With Nonlytic Interleukin 2/Fc Fusion Protein Improves Immune Response to Hepatitis B Vaccination in a Mouse Skin Transplantation Model [5]中国肾移植受者环孢霉素的治疗窗 [6]Optimization for Cyclosporine Blood Concentration Prediction Based on Genetic Algorithm - BP Neural Network [7]Effects of nicardipine on blood cyclosporine levels in renal transplant patients [8]环孢菌素致肝毒性反应的回顾性分析 [9]肾移植术后西罗莫司联合减量或停用环孢素A的应用体会 [10]Outcomes of Pediatric Liver Transplantation: Deceased Donor Liver Transplantation vs Living Donor Liver Transplantation