单位：[1]Hong Kong Univ Sci & Technol, Dept Biol, Hong Kong, Hong Kong, Peoples R China[2]Capital Univ Med Sci, Beijing Friendship Hosp, Beijing 100050, Peoples R China首都医科大学附属北京友谊医院[*1]Hong Kong Univ Sci & Technol, Dept Biol, Clear Water Bay Rd, Hong Kong, Hong Kong, Peoples R China
Danggui Buxue Tang (DBT) is prepared from Radix Astragali and Radix Angelicae Sinensis. This Chinese herbal decoction has been shown to stimulate the proliferation of T-lymphocytes; however, the action mechanism of this stimulation has not been revealed. In cultured T-lymphocytes, application of DBT markedly induced the cell proliferation, the release of interleukin-2, -6 and -10, as well as the phosphorylation of extracellular signal-regulated kinases (ERK). The pre-treatment of ERK inhibitor blocked the DBT-induced immune responses. In addition, the polysaccharide-enriched fraction of DBT showed marked responses on the cultured T-lymphocytes suggesting the important role of DBT polysaccharide in triggering such immune responses. (C) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
通讯机构：[*1]Hong Kong Univ Sci & Technol, Dept Biol, Clear Water Bay Rd, Hong Kong, Hong Kong, Peoples R China
推荐引用方式(GB/T 7714)：
Gao Qiu T.,Cheung Jerry K. H.,Li Jun,et al.A chinese herbal decoction, danggui buxue tang, activates extracellular signal-regulated kinase in cultured T-lymphocytes[J].FEBS LETTERS.2007,581(26):5087-5093.doi:10.1016/j.febslet.2007.09.053.
APA：
Gao, Qiu T.,Cheung, Jerry K. H.,Li, Jun,Jiang, Zhi Y.,Chu, Glanice K. Y....&Tsim, Karl W. K..(2007).A chinese herbal decoction, danggui buxue tang, activates extracellular signal-regulated kinase in cultured T-lymphocytes.FEBS LETTERS,581,(26)
MLA：
Gao, Qiu T.,et al."A chinese herbal decoction, danggui buxue tang, activates extracellular signal-regulated kinase in cultured T-lymphocytes".FEBS LETTERS 581..26(2007):5087-5093
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