单位：[1]CNRS, UMR 7563, LEMTA, F-54500 Vandoeuvre Nancy, France[2]Res Inst China Japan Friendship Hosp, Beijing 100029, Peoples R China[*1]CNRS, UMR 7563, LEMTA, 2 Av Foret Haye, F-54500 Vandoeuvre Nancy, France
The aim of this work is to study the deformability of red blood cells (RBC) by two laser diffraction methods: the Laser-assisted Optical Rotational Cell Analyser (LORCA, Mechatronics, Amsterdam, Netherlands) and a Shear Stress Diffractometer (RHEODYN SSD, Myrenne, Roetgen, Germany). Experiments were carried out on 46 healthy human subjects. The elongation index EI of normal and hardened RBCs (obtained by heating blood at 49 degrees C or by incubating RBCs in solutions of diamide) was measured. The results showed that the standard deviations of the experimental data for normal RBCs were relatively small, especially at high shear stresses (more than 3.0 Pa), but higher than those reported before. Some correlations between the results given by the two instruments were also found. It should be noted that for hardened RBCs, the standard deviations of the measurements were important compared with the mean values in the two instruments.
第一作者单位：[*1]CNRS, UMR 7563, LEMTA, 2 Av Foret Haye, F-54500 Vandoeuvre Nancy, France
通讯作者：
通讯机构：[*1]CNRS, UMR 7563, LEMTA, 2 Av Foret Haye, F-54500 Vandoeuvre Nancy, France
推荐引用方式(GB/T 7714)：
Wang X,Zhao H,Zhuang FY,et al.Measurement of erythrocyte deformability by two laser diffraction methods[J].CLINICAL HEMORHEOLOGY and MICROCIRCULATION.1999,21(3-4):291-295.
APA：
Wang, X,Zhao, H,Zhuang, FY&Stoltz, JF.(1999).Measurement of erythrocyte deformability by two laser diffraction methods.CLINICAL HEMORHEOLOGY and MICROCIRCULATION,21,(3-4)
MLA：
Wang, X,et al."Measurement of erythrocyte deformability by two laser diffraction methods".CLINICAL HEMORHEOLOGY and MICROCIRCULATION 21..3-4(1999):291-295
