Objective To explore whether protective ileostomy is beneficial in preventing anastomotic leakage after anterior resection of rectal cancer. Methods A total of 347 patients underwent anterior resection of rectal cancer in our hospital. Ninety-five patients were treated with protective ileostomy (treatment group), and 252 patients were not (control group). The incidences of anastomotic leakage and permanent stoma were compared between the two groups. Results The overall incidences of anastomotic leakage were 6.32% (6/95) and 8.73% (22/252) in the treatment group and control group, respectively. In the cohort of patients who underwent neoadjuvant radiotherapy, the incidence of anastomotic leakage was 5.88% (2/34) and 12.0% (3/25) in the treatment group and control group, respectively. Logistic regression showed that the incidence of anastomotic leakage was not statistically significant. However, diabetes and the anastomotic height significantly affected the occurrence of anastomotic leakage. The permanent stoma rate was 6.42% (6/95) and 5.95% (15/252) in the treatment group and control group, respectively. Conclusion Protective ileostomy did not show a significant advantage in reducing the incidence of postoperative anastomotic leakage in patients with rectal cancer, and it may lead to a permanent stoma.
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外文
被引次数：
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PubmedID：
中科院(CAS)分区：
出版当年[2019]版：
大类|4 区医学
小类|4 区医学：研究与实验4 区药学
最新[2025]版：
大类|4 区医学
小类|4 区医学：研究与实验4 区药学
JCR分区：
出版当年[2018]版：
Q4PHARMACOLOGY & PHARMACYQ4MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版：
Q4MEDICINE, RESEARCH & EXPERIMENTALQ4PHARMACOLOGY & PHARMACY
第一作者单位：[1]Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China
通讯作者：
通讯机构：[1]Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China[*1]Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, 95 Yong An Road, Beijing 100050, China.
推荐引用方式(GB/T 7714)：
Niu Lei,Wang Jin,Zhang Peng,et al.Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer[J].JOURNAL of INTERNATIONAL MEDICAL RESEARCH.2020,48(8):doi:10.1177/0300060520946520.
APA：
Niu, Lei,Wang, Jin,Zhang, Peng&Zhao, Xiaomu.(2020).Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer.JOURNAL of INTERNATIONAL MEDICAL RESEARCH,48,(8)
MLA：
Niu, Lei,et al."Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer".JOURNAL of INTERNATIONAL MEDICAL RESEARCH 48..8(2020)
