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Adult Body Height and Cardiometabolic Disease Risk: The China National Health Survey in Shaanxi

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单位: [1]Graduate School, Beijing University of Chinese Medicine, Beijing, China [2]International Medical Services, China- Japan Friendship Hospital, Beijing, China [3]Department of Pediatrics, Oriental Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China [4]Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China
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关键词: body height cardiometabolic disease adult optimal model risk prediction

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Objectives Based on data from the China National Health Survey, we aimed to examine the association between body height and cardiometabolic disease (CMD) in a large adult population from Shaanxi province, and further to test whether this association was hinged upon other population characteristics. Methods This population-based study was conducted in 2014 in Shaanxi Province, China. Utilizing a multi-stage stratified cluster sampling method, total 5,905 adults with complete data were eligible for analysis, and 1,151 (19.5%) of them had CMD. Of 1,151 CMD patients, 895 (15.1%) had one disorder and 256 (4.4%) had >= 2 disorders. Results Using the bi-directional stepwise method and all-subsets regression, five factors-age, body mass index, family histories of CMD, exercise, and height-constituted the optimal model when predicting CMD risk. Restricted cubic spline regression showed a reduced tendency towards CMD with the increase of body height, with per 10 cm increment in body height corresponding to 14% reduced risk. Ordinal Logistic regression supported the contribution of body height on both continuous and categorical scales to CMD risk before and after adjustment, yet this contribution was significantly confounded by exercise and education, especially by exercise, which can explain 65.4% of total impact. For example, short stature was associated with an increased risk of CMD after multivariable adjustment not including exercise and education (odds ratio, 95% confidence interval, P: 1.42, 1.21 to 1.66, <0.001), and tall stature was associated with a reduced risk (0.77, 0.64 to 0.92, 0.003). Conclusions Our findings indicate short stature was a risk factor, yet tall stature was a protective factor for CMD in Chinese. Notably, the prediction of short and tall stature for CMD may be mediate in part by exercise.

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出版当年[2019]版:
大类 | 2 区 医学
小类 | 3 区 内分泌学与代谢
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 内分泌学与代谢
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出版当年[2018]版:
Q2 ENDOCRINOLOGY & METABOLISM
最新[2023]版:
Q2 ENDOCRINOLOGY & METABOLISM

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第一作者单位: [1]Graduate School, Beijing University of Chinese Medicine, Beijing, China [2]International Medical Services, China- Japan Friendship Hospital, Beijing, China
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