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Validity and Reliability of the New Chinese Version of the Frontal Assessment Battery-Phonemic

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单位: [1]Department of Cognitive Disorder, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. [2]China National Clinical Research Center for Neurological Diseases, Beijing, China. [3]Medical School, Xizang Minzu University, Xianyang, China. [4]Department of Neurology, China-Japan Friendship Hospital, Beijing, China.
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关键词: Alzheimer's disease dementia Frontal Assessment Battery mild cognitive impairment phonetics

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Background: Alzheimer's disease dementia (ADD) is an important health problem in the world. Objective: The present study investigated the validity and reliability of a new version of the Frontal Assessment Battery (FAB) named the FAB-phonemic (FAB-P). Methods: A total of 76 patients with ADD, 107 patients with amnestic mild cognitive impairment (aMCI), 37 patients with non-amnestic MCI (naMCI), and 123 healthy controls were included in this study. All participants were evaluated with the FAB-P and the cognitive assessments according to a standard procedure. Results: The global FAB-P scores in patients withADDwere lower than those of patients with aMCI, patients with naMCI, and healthy controls (p < 0.001). Patients with aMCI performed worse than healthy controls (p < 0.001). The interrater reliability, test-retest reliability, and Cronbach's alpha coefficient for the FAB-P were 0.997, 0.819, and 0.736, respectively. The test could distinguish the patients with mild ADD, aMCI, and naMCI from healthy controls with classification accuracy of 89.4%, 70.9%, and 61.6%, respectively. It could also discriminate between the patients with ADD and aMCI, between those with ADD and naMCI, and between those with aMCI and naMCI with classification accuracy of 73.8%, 83.9%, and 58.0%, respectively. The regression analysis revealed that the Montreal Cognitive Assessment and the Stroop Color Word Test Part C had the greatest contribution to FAB-P score variance. Conclusion: The FAB-P is a valid and reliable tool for evaluating frontal lobe function and can effectively discriminate ADD, aMCI, and naMCI.

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出版当年[2020]版:
大类 | 2 区 医学
小类 | 3 区 神经科学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 神经科学
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出版当年[2019]版:
Q2 NEUROSCIENCES
最新[2023]版:
Q2 NEUROSCIENCES

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2019版] 出版当年五年平均[2015-2019] 出版前一年[2018版] 出版后一年[2020版]

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第一作者单位: [1]Department of Cognitive Disorder, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. [2]China National Clinical Research Center for Neurological Diseases, Beijing, China. [*1]Department of Cognitive Disorder, Beijing Tiantan Hospital, Capital Medical University, Fengtai District, South 4th Ring Road West 119, Beijing 100070, China
通讯作者:
通讯机构: [1]Department of Cognitive Disorder, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. [2]China National Clinical Research Center for Neurological Diseases, Beijing, China. [*1]Department of Cognitive Disorder, Beijing Tiantan Hospital, Capital Medical University, Fengtai District, South 4th Ring Road West 119, Beijing 100070, China
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