单位：[1]School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China[2]Department of Traditional Chinese Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China临床科室中医科中医科首都医科大学附属北京友谊医院[3]Institute of Acupuncture & Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China
Acute myeloid leukemia (AML) is a hematological malignancy, which is commonly associated with high incidence and mortality among adult patients. The standard induction regimen for AML has been substantially unchanged over the past 40 years, for which novel nanomedicines have represented a promising strategy in AML therapies. Despite developments of multiple nanoparticles formulated with drugs or genes, less there is not much information available about approaches in AML is available. This review presents an overview of nanomedicines currently being evaluated in AML. First, it briefly summarized conventional chemotherapies in use. Second, nanomedicines presently ongoing in clinical trials or preclinical researches were classified and described, with illustrative examples from recent literatures. Finally, limitations and potential safety issues concerns in clinical translation of AML treatment were discussed as well.
基金：
Hong Kong Baptist University Special Development Fund [SDF18-0319-P03]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2018]版：
大类|4 区医学
小类|3 区核医学4 区药学
最新[2025]版：
大类|4 区医学
小类|4 区药学4 区核医学
JCR分区：
出版当年[2017]版：
Q2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGINGQ3PHARMACOLOGY & PHARMACY
最新[2023]版：
Q2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGINGQ3PHARMACOLOGY & PHARMACY
第一作者单位：[1]School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
通讯作者：
通讯机构：[1]School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China[*1]School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China.
推荐引用方式(GB/T 7714)：
Xiao Huang,Hai Lin,Feng Huang,et al.Targeting Approaches of Nanomedicines in Acute Myeloid Leukemia[J].DOSE-RESPONSE.2019,17(4):doi:10.1177/1559325819887048.
APA：
Xiao Huang,Hai Lin,Feng Huang,Yuning Xie,Ka Hong Wong...&Zhijun Yang.(2019).Targeting Approaches of Nanomedicines in Acute Myeloid Leukemia.DOSE-RESPONSE,17,(4)
MLA：
Xiao Huang,et al."Targeting Approaches of Nanomedicines in Acute Myeloid Leukemia".DOSE-RESPONSE 17..4(2019)
